The Monitoring of Persistent Toxic Substances
by Different Analytical Approaches

 

Ramaswamy Babu Rajendran

Department of Eco-Biotechnology, School of Environmental Sciences

Bharathidasan University

 

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Widespread contamination of biosphere by number of anthropogenic chemicals resulted in some impact on wildlife and humans. Most of the synthetic organic pollutants are environmentally persistent, non-biodegradable, bioaccumulative and endocrine disrupting in behaviour. Endocrine disrupting persistent toxic substances such as organochlorines, organotins and organobromines have been reported from all over the globe for the past few decades. There are several approaches to measure the chemical contaminants in environment. Combinations of bio/chemical analytical tools will help to solve problems associated with the detection of persistent pollutants of endocrine disrupting in nature. It is unlikely that the biochemical screening methods will ever replace chemical instrumental analysis or in vivo toxicological studies, but could compliment these two. Environmental monitoring of contaminants by coupled instruments like GC/MS and GC/ICPMS, etc has enabled to measure a wide range of pollutants both quantitatively and qualitatively, and with high selectivity and sensitivity even up to femtogram level.

 

The analysis of organic compounds from aqueous sample matrices can be performed by a combination of various extraction and analytical methods. The extraction methods employed with liquid samples include liquid-liquid extraction, solid phase extraction (SPE), and headspace and purge-and-trap techniques. A new extraction technique known as solid-phase microextraction (SPME) is being used for the past several years. SPME combined with GC and LC is widely in use. Apart from SPME, sorptive techniques for sample enrichment have been performed since the 1980s. More rapid and less solvent-dependent techniques have been developed for extraction of analytes including accelerated solvent extraction (ASE) for solids (soil, sediment, biota, food commodities etc.). ASE at elevated pressure and temperature is an efficient and automated alternative to soxhlet extraction of nonpolar contaminants such as organochlorine insecticides, etc. The related technique of microwave assisted solvent extraction also gave high recoveries of these contaminants. Programmed temperature vaporizer (PTV) system helps to quantify ultra trace levels by injecting large volume of sample extracts. The use of isotope-labelled internal standards and surrogates greatly increases the precision and accuracy.

 

Quantification of organotins in open ocean water by PTV-GC/ICPMS, and brominated flame retardants (PBDEs) in marine and riverine sediments by GC/ICPMS, and the efficiency of two different extraction (soxhlet and microwave) techniques will be discussed.